NOVACOR WELCOME CLINICAL APPLICATIONS MEASUREMENT PRECISION
CLINICAL APPLICATIONS

Measurement precision

Twenty-four-hour ambulatory blood pressure monitoring in atrial fibrillation

Clinical evaluation of the Diasys Integra blood pressure recorder

The Importance of 24 Hour Ambulatory Blood Pressure Monitoring After Thoracic Organ Transplantation

Blood pressure measurement

Twenty-four-hour ambulatory blood pressure monitoring in atrial fibrillation

Roy Olsen, Aina Amlie and Per Omvik.
Institute for Internal Medicine, Department of Heart Disease, Haukeland
Hospital, 5021 Bergen, Norway.


Background
Due to large beat-to-beat blood pressure variation the use of 24-h ambulatory blood pressure monitoring in patients with atrial fibrillation has been questioned.


Methods
Repeatability and variability of 24-h ambulatory blood pressure (Accutraccer II or Diasys Integra), and daily blood pressure variation was examined in 42 patients aged 51–81 (median 73.5) years admitted for elective electrocardioversion of atrial fibrillation.


Results
Before cardioversion 24-h ambulatory systolic blood pressure was slightly lower and nocturnal blood
pressure reduction was larger in the group of patients who achieved sinus rhythm than in the group who
maintained atrial fibrillation (11.5/10.5 versus 4.1/4.7 mmHg; Po0.05). No statistically significant change
was observed in ambulatory blood pressure after cardioversion in any of the two groups. Blood pressure
variability (SD/mean) was 10–14% both in patients with and without conversion to sinus rhythm. Coefficient of repeatability (2SD of difference) was 13.6mmHg (16.6%) for diastolic blood pressure and 30.2mmHg (24.7%) for systolic blood pressure in patients with normalized heart rhythm and 17.0 and 29.0mmHg (21.5 and 22.4%) in patients with maintained atrial fibrillation, respectively.

Conclusion
Ambulatory blood pressure monitoring provides data with similar variability and repeatability in patients with atrial fibrillation as in subjects with normal cardiac rhythm. Twenty-four-hour ambulatory blood
pressure measurement is applicable in atrial fibrillation in the same way as during sinus rhythm.
Blood Press Monit 7: 149–156 & 2002 Lippincott Williams & Wilkins.

Download the article (.PDF)

Blood Pressure Monitoring 2002, 7:149^156
Keywords: ambulatory blood pressure monitoring, atrial fibrillation,
cardioversion, nocturnal dip, repeatability, variability

TOP OF PAGE


Clinical evaluation of the Diasys Integra blood pressure recorder

Philippe Gosse, Albert Laforge, Véronique Jullien, Pascal Ansoborlo,
Philippe Lemetayer, Jacques Clementy
CHU Bordeaux, Hôpital Saint André, 1 rue Jean Burguet, 33075 Bordeaux


Objective: The Diasys Integra (NOVACOR, France) is a new lightweight (<200g) non-invasive, programmable portable blood pressure recorder with both auscultatory and oscillometric measurement of BP. This study was designed to check its accuracy in rest condition.

Method: Blood pressure was measured simultaneously on the same arm in the sitting position by a trained observer with a mercury sphygmomanometer and by the Diasys Integra. Three pairs of measurement were performed for auscultatory and oscillometric methods. The deflation rate programmed for this protocol was 5mmHg/step. This protocol was performed in 100 patients admitted in a cardiology unit. The level of agreement between the observer and the device was assessed by calculating the percentages of all determinations within 5 and 10 mmHg of each other.

Results: The study included 100 patients aged 65±15 years (ranging 23 to 96 years), 60 males and 40 females. Observer BP range was: 78 to 226 (mean=134±23 mmHg) for SBP, 48-140 (mean=79±16 mmHg) for DBP.

RESULTS


         OBS    DIASYS     r   DIFF   RANGE  <5  <10   <15
Ausc
SBP  133+-23  130+-23  0.97  3+-5   -23à27  76%  90%  95%  B
DBP   79+-16   78+-15  0.97  1+-4    -5à27  90%  98%  98%  A

Oscil
SBP 
135+-21  134+-20  0.97  1+-5   -13à14  75%  96% 100%  B
DBP
   77+-15   76+-15  0.92  1+-6   -26à17  78%  92%  96%  B
 

The 3 mmHg underestimation of SBP with the auscultatory method may be due to the deflation rate chosen in this protocol (5mm/step).

Conclusion: The Diasys Integra achieved at least a B rating according to the criteria of the British Hypertension Society protocol. Results are better with auscultatory method for DBP. A trend to SBP underestimation by the device with auscultatory method may be linked to the deflation rate used in this protocol (5mm/step) and may be corrected.

TOP OF PAGE

The Importance of 24 Hour Ambulatory Blood Pressure Monitoring After Thoracic Organ Transplantation

Antony Hayden Walker, MBChB, FRCS, Timothy J. Locke, MD, FRCS, Peter C. Braidley, FRCS, and Abdullah Al-Mohammed, MD, MRCP

Background
Hypertension is a significant complication after thoracic organ transplantation. In the non-transplant
population, 24-hour ambulatory blood pressure monitoring (24ABPM) is useful in the diagnosis of
white-coat hypertension, the assessment of resistant hypertension, and the monitoring of anti-hypertensive
therapy. The loss of nocturnal reductions in blood pressure is associated with hypertensive
end-organ damage. This study investigated the role of 24ABPM after orthotopic cardiac transplantation.

Methods
Thirty-three transplant recipients underwent 24ABPM. Clinical blood pressure (CPB) was measured
by using a sphygmomanometer before 24ABPM. Clinical data were collected and analyzed by a
single observer with p values of less than 0.05 being taken as significant.

Results
The incidence of hypertension (diastolic pressure  90 mm Hg) in the CPB and 24ABPM groups was
33% and 52% (p 0.002). Thirty-two percent of recipients who were normotensive by clinical
measurement were found to be hypertensive after 24ABPM. The converse was true in 1 case. We
identified no specific risk factors for 24ABPM hypertension. One recipient failed to complete the
24-hour monitoring period.

Conclusion
This study demonstrates that conventional blood pressure monitoring underestimates the incidence of
post-transplantation hypertension. Twenty-four hour ambulatory blood pressure monitoring is well
tolerated and may improve the management of post-transplantation hypertension. White-coat hypertension
is an uncommon diagnosis after cardiac transplantation, and those recipients who are hypertensive
in the clinic setting should be considered true hypertensives. J Heart Lung Transplant 2005;24:1770–3.
Copyright © 2005 by the International Society for Heart and Lung Transplantation.

TOP OF PAGE

Blood pressure measurement

Part III - Automated sphygnomanometry: ambulatory blood pressure measurement

Eoin O’Brien, Gareth Beevers, Gregory Y H Lip

In recent years, the accuracy of the conventional Riva-Rocci/Korotkoff technique of blood pressure measurement has been questioned and efforts have been made to improve the technique with automated devices. In the same period, recognition of the phenomenon of white coat hypertension, whereby some subjects with apparent elevation of blood pressure have normal, orreduced, blood pressures whets measurement is repeated away front the medical environment, has focused attention on methods of measurement that provide profiles of blood pressure behaviour rather than relying on isolated measurements under circumstances that may in themselves influence the level of blood pressure recorded.

These methodologies have included repeated measurements of blood pressure using the traditional technique, self measurement of blood pressure in the home or workplace, and ambulatory bloodpressure measurement (ABPM) using innovative automated devices)

British Medical Journal 322, p. 1110-1114, 2001

TOP OF PAGE